John Pool Postdoctoral Researcher Population Genetics jpool (at) berkeley.edu |  |
CV (pdf) Links to publications | |
Affiliations: | |
| University of California, Berkeley Department of Integrative Biology Rasmus Nielsen's Group | University of California, Davis Center for Population Biology Drosophila Population Genomics Group (Chuck Langley and colleagues) |
| Research Interests: |
 A tidal wave of population genomic data. | New inference methods for population genomic data sets: Building on my previous empirical and theoretical investigations of the effects of population history on genetic variation, I am developing new population genetic analysis methods for genome-scale data sets. These methods incorporate unique aspects of this data, such as long-range haplotypes and complementary information from X-linked and autosomal loci. Another approach is aimed at accurate historical inference in the presence of pervasive positive and negative selection. |
| The genetic basis of parallel melanic evolution in Drosophila: My past research has documented striking melanic phenotypes among Drosophila melanogaster from the highlands of sub-Saharan Africa, a pattern partially driven by adaptive change in the regulatory region of ebony. And a recent study has uncovered the precise mutational and regulatory basis of phenotypic change at this gene. But the genetic basis of melanic evolution appears to be geographically variable, and ongoing work seeks to identify the genetic basis of parallel phenotypic changes in this model system. |  Melanic melanogaster from African highlands. |