The POOL Lab

Research    People    Publications    Genomes

Why Study Population Genetics?   Why Flies?

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The Pool lab's research is in two related areas:

Genetic Basis of Adaptive Evolution

Drosophila melanogaster provides an excellent model system for learning about the genes and mutations that underpin adaptive phenotypic changes.  Our ongoing work investigates the genetic basis of body size, cold tolerance, and pigmentation differences within this species. Each of these traits shows patterns of parallel evolution associated with high altitude.

Melanic melanogaster from African highlands
A tidal wave of population genomic data Analysis of Population Genomic Data

"Next-generation sequencing" has revolutionized our field by allowing us to study genetic variation at the scale of fully sequenced genomes.  We develop new statistical methods for population genomics, and we analyze data to gain biological insights regarding the targets of natural selection and the histories of populations.  

Research     People     Publications     Why Study Population Genetics?

Contact Info    Genomes    Why Flies?    Journal Club    Want to Join?